Science-Backed Lion’s Mane

The Research Behind Lion’s Mane

Explore published studies on cognition, mood, neuroprotection, and more.

Important note: Our products are not intended to diagnose, treat, cure, or prevent any disease. Lion’s Mane is not a substitute for medical advice. Consult a healthcare professional before use.

Cognition & Memory

Preclinical

Hericerin derivatives activates a pan-neurotrophic pathway enhancing spatial memory

 Human clinical trial

Improving effects of Hericium erinaceus on mild cognitive impairment

 Pilot study

Prevention of early Alzheimer's disease using Erinacine A enriched Lion’s Mane

 Human study

Improvement of cognitive functions by oral intake of Lion’s Mane

 Pilot study

Effects of Lion’s Mane supplementation on cognition, stress, and mood

Mood & Stress

Human study

Reduction of depression and anxiety after Lion’s Mane intake

 Pilot study

Effects on stress and mood in young adults

 Preclinical

Anxiolytic effects in tau mouse model

Neuroprotection & Other Research

Review

Neuroregenerative potential of Lion’s Mane

 Preclinical

Antioxidant activity of Lion’s Mane polysaccharides

 Preclinical

Inhibition of cancer metastasis in mouse model

 Preclinical

Neurotrophic properties of Lion’s Mane

 Preclinical

Reduction of oxidative damage and inflammation in neural cells